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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|RUNX1 - RUNX1T1 KIT mut||acute myeloid leukemia||not applicable||N/A||Clinical Study||Prognostic||In clinical analyses, coincident KIT mutations were associated with higher relapse rate and decreased overall survival in acute myeloid leukemia patients with RUNX1-RUNX1T1 fusions (PMID: 18648004, PMID: 16384925, PMID: 25111512).||25111512 16384925 18648004|
|PubMed Id||Reference Title||Details|
|(18648004)||Clinical significance of the most common chromosome translocations in adult acute myeloid leukemia.||Full reference...|
|(25111512)||Identification of molecular and cytogenetic risk factors for unfavorable core-binding factor-positive adult AML with post-remission treatment outcome analysis including transplantation.||Full reference...|
|(16384925)||Prognostic impact of c-KIT mutations in core binding factor leukemias: an Italian retrospective study.||Full reference...|