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Molecular Profile RUNX1 - RUNX1T1 KIT mut
Therapy N/A
Indication/Tumor Type acute myeloid leukemia
Response Type not applicable

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
RUNX1 - RUNX1T1 KIT mut acute myeloid leukemia not applicable N/A Clinical Study Prognostic In clinical analyses, coincident KIT mutations were associated with higher relapse rate and decreased overall survival in acute myeloid leukemia patients with RUNX1-RUNX1T1 fusions (PMID: 18648004, PMID: 16384925, PMID: 25111512). 25111512 16384925 18648004
PubMed Id Reference Title Details
(18648004) Clinical significance of the most common chromosome translocations in adult acute myeloid leukemia. Full reference...
(25111512) Identification of molecular and cytogenetic risk factors for unfavorable core-binding factor-positive adult AML with post-remission treatment outcome analysis including transplantation. Full reference...
(16384925) Prognostic impact of c-KIT mutations in core binding factor leukemias: an Italian retrospective study. Full reference...