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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|CEBPA mutant||acute myeloid leukemia||not applicable||N/A||Guideline||Prognostic||CEBPA biallelic mutations are associated with a favorable prognosis in patients with non-APL acute myeloid leukemia (NCCN.org).||detail...|
|CEBPA mutant||acute myeloid leukemia||not applicable||N/A||Clinical Study||Prognostic||In clinical analyses, biallelic CEBPA mutations were associated with favorable clinical outcome in patients with cytogenetically normal acute myeloid leukemia (PMID: 26601784, PMID: 19171880, PMID: 20038735, PMID: 22915647).||22915647 26601784 19171880 20038735|
|PubMed Id||Reference Title||Details|
|(26601784)||The multifaceted functions of C/EBPα in normal and malignant haematopoiesis.||Full reference...|
|(19171880)||Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favorable outcome.||Full reference...|
|(20038735)||Acute myeloid leukemia with biallelic CEBPA gene mutations and normal karyotype represents a distinct genetic entity associated with a favorable clinical outcome.||Full reference...|
|(22915647)||A novel hierarchical prognostic model of AML solely based on molecular mutations.||Full reference...|