Profile Response Detail

Molecular Profile KRAS mutant
Therapy Erlotinib
Indication/Tumor Type lung adenocarcinoma
Response Type resistant
Create By rliu
Update By spatt


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
KRAS mutant lung adenocarcinoma resistant Erlotinib Clinical Study Actionable In a clinical study, KRAS mutations were associated with resistance to Tarceva (erlotinib) in patients with lung adenocarcinoma (PMID: 15696205). 15696205
PubMed Id Reference Title Details
(15696205) KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. Full reference...