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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|KIT act mut||Advanced Solid Tumor||sensitive||PLX9486||Preclinical||Actionable||In a preclinical study, PLX9486 inhibited KIT mutations, including exon 17 mutations, and demonstrated in vivo and in vitro activity against tumors harboring KIT exon 17 mutations (Cancer Res February 1, 2016 76; IA32).||detail...|
|PubMed Id||Reference Title||Details|
|Optimizing kinase inhibitors to treat cancer||Full reference...|