Profile Response Detail

Molecular Profile SMO dec exp
Therapy SANT1
Indication/Tumor Type osteosarcoma
Response Type predicted - sensitive
Create By tyin
Update By djd


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
SMO dec exp osteosarcoma predicted - sensitive SANT1 Preclinical Actionable In a preclinical study, SANT1 inhibited survival of osteosarcoma cell lines with reduced SMO mRNA level in culture (PMID: 26781311). 26781311
PubMed Id Reference Title Details
(26781311) Targeting hedgehog signaling pathway in pediatric tumors: in vitro evaluation of SMO and GLI inhibitors. Full reference...