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Molecular Profile Unknown unknown
Therapy Denosumab
Indication/Tumor Type bone giant cell tumor
Response Type not applicable


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown bone giant cell tumor not applicable Denosumab FDA approved Actionable In a Phase II clinical trial that supported FDA approval, Xgeva (denosumab) treatment resulted in an overall objective response rate of 25% (47/187) in patients with giant cell bone tumor, with a median duration of response of 20 months among patients demonstrating response (PMID: 25617146). detail... 25617146
PubMed Id Reference Title Details
(25617146) Giant cell tumour of bone: new treatments in development. Full reference...
Xgeva (denosumab) FDA Drug Label Full reference...