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|Molecular Profile||FGFR1 amp|
|Indication/Tumor Type||breast cancer|
|Response Type||no benefit|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|FGFR1 amp||breast cancer||no benefit||AZD4547||Phase II||Actionable||In a Phase II clinical trial, treatment with AZD4547 resulted in a response rate of 12.5% (1/8) in patients with FGFR1-amplified breast cancer, and did not meet the predetermined criteria for efficacy (PMID: 27179038).||27179038|
|PubMed Id||Reference Title||Details|
|(27179038)||High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial.||Full reference...|