Profile Response Detail

Molecular Profile Unknown unknown
Therapy Bleomycin + CBP501
Indication/Tumor Type colorectal cancer
Response Type not applicable
Create By spatt
Update By spatt

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown colorectal cancer not applicable Bleomycin + CBP501 Preclinical - Cell line xenograft Actionable In a preclinical study, treatment with the combination of Blenoxane (bleomycin) and CBP501 resulted in enhanced tumor growth inhibition in cell line xenograft models of colorectal cancer, compared to either agent alone (PMID: 17237275). 17237275
PubMed Id Reference Title Details
(17237275) Cell cycle phenotype-based optimization of G2-abrogating peptides yields CBP501 with a unique mechanism of action at the G2 checkpoint. Full reference...