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Molecular Profile Unknown unknown
Therapy Napabucasin
Indication/Tumor Type colorectal cancer
Response Type not applicable


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown colorectal cancer not applicable Napabucasin Phase I Actionable In a Phase I trial, colorectal cancer patients treated with BBI608 demonstrated a median PFS of 14 weeks and OS of 47 months while 67% (8/12) experienced stable disease (J Clin Oncol May 2013 vol. 31 no. 15_suppl 2542). detail...
PubMed Id Reference Title Details
A dose-escalation phase I study of a first-in-class cancer stemness inhibitor in patients with advanced malignancies Full reference...