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Molecular Profile Unknown unknown
Therapy Fluorouracil + Leucovorin + Oxaliplatin + Tivozanib
Indication/Tumor Type colorectal cancer
Response Type no benefit

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown colorectal cancer no benefit Fluorouracil + Leucovorin + Oxaliplatin + Tivozanib Phase II Actionable In a Phase II trial, the combination of mFOLFOX-6 and Tivozanib (AV-951) in patients with metastatic colorectal cancer did not result in a greater progression free survival when compared to the combined therapy of mFOLFOX-6 and Avastin (bevacizumab) (9.8 vs 9.5 mo, respectively) (PMID: 27401244). 27401244
PubMed Id Reference Title Details
(27401244) BATON-CRC: A Phase II Randomized Trial Comparing Tivozanib Plus mFOLFOX6 with Bevacizumab Plus mFOLFOX6 in Stage IV Metastatic Colorectal Cancer. Full reference...