Profile Treatment Approach Detail

Profile Treatment Approach Name mTORC1 Inhibitor
Profile Name FBXW7 Q47*
Drug Class mTORC1 Inhibitor 8
Therapy

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PubMed Id Reference Title Details
(18787170) FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression. Full reference...
(24586741) FBXW7 mutations in patients with advanced cancers: clinical and molecular characteristics and outcomes with mTOR inhibitors. Full reference...