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Profile Treatment Approach Name PIK3CB inhibitor
Profile Name PTEN loss
Drug Class PIK3CB inhibitor 8
Therapy

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PubMed Id Reference Title Details
(23674493) PI3K pathway dependencies in endometrioid endometrial cancer cell lines. Full reference...
(25514658) Discovery of (R)-8-(1-(3,5-difluorophenylamino)ethyl)-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide (AZD8186): a potent and selective inhibitor of PI3Kβ and PI3Kδ for the treatment of PTEN-deficient cancers. Full reference...
(26645196) Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy. Full reference...