Profile Treatment Approach Detail

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Profile Treatment Approach Name FGFR Inhibitor (Pan)
Profile Name FGFR2 fusion
Drug Class FGFR Inhibitor (Pan) 23
Therapy

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PubMed Id Reference Title Details
(28416604) Oncogenic Characterization and Pharmacologic Sensitivity of Activating Fibroblast Growth Factor Receptor (FGFR) Genetic Alterations to the Selective FGFR Inhibitor Erdafitinib. Full reference...
(31088831) Multicenter Phase I Study of Erdafitinib (JNJ-42756493), Oral Pan-Fibroblast Growth Factor Receptor Inhibitor, in Patients with Advanced or Refractory Solid Tumors. Full reference...
Final results from a phase II study of infigratinib (BGJ398), an FGFR-selective tyrosine kinase inhibitor, in patients with previously treated advanced cholangiocarcinoma harboring an FGFR2 gene fusion or rearrangement. Full reference...