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|Profile Treatment Approach Name||mTORC1 Inhibitor|
|Profile Name||FBXW7 R465C|
|Drug Class||mTORC1 Inhibitor 9|
|PubMed Id||Reference Title||Details|
|(18787170)||FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression.||Full reference...|
|(24586741)||FBXW7 mutations in patients with advanced cancers: clinical and molecular characteristics and outcomes with mTOR inhibitors.||Full reference...|