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Ref Type Journal Article
PMID (23733758)
Authors Peters S, Michielin O, Zimmermann S
Title Dramatic response induced by vemurafenib in a BRAF V600E-mutated lung adenocarcinoma.
Journal Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Vol 31
Issue 20
Date 2013 Jul 10
URL
Abstract Text

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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
Drug Name Trade Name Synonyms Drug Classes Drug Description
Gene Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
BRAF V600E lung non-small cell carcinoma sensitive Vemurafenib Case Reports/Case Series Actionable In a clinical case study, a non-small cell lung cancer patient harboring a BRAF V600E mutation had a complete response after treatment with Zelboraf (vemurafenib) (PMID: 23733758). 23733758