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Authors | B Moreau, R Alargova, A Brockman, K Whalen, J Quinn, K Meetze, P Bazinet, M DuPont, B Krawiec, K Kriksciukaite, C Lemelin, P LimSoo, H Oller, M Ramstack, D Rockwood, R Shinde, S Singh, B White, T AuYeung, C Dunbar, M Bilodeau, R Wooster | ||||||||||||
Title | BTP-114: An albumin binding cisplatin prodrug with improved and sustained tumor growth inhibition | ||||||||||||
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URL | http://cancerres.aacrjournals.org/content/75/15_Supplement/4484 | ||||||||||||
Abstract Text | Cancer Res 2015;75(15 Suppl):Abstract nr 4484 |
Molecular Profile | Treatment Approach |
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Gene Name | Source | Synonyms | Protein Domains | Gene Description | Gene Role |
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Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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BTP-114 | BTP 114 | BTP-114 is a prodrug of cisplatin that has prolonged plasma circulation time and increased tumor distribution, which leads to improved anti-tumor activity (Cancer Res 2015;75(15 Suppl):Abstract nr 4484). |
Gene | Variant | Impact | Protein Effect | Variant Description | Associated with drug Resistance |
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Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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