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Ref Type
PMID
Authors B Moreau, R Alargova, A Brockman, K Whalen, J Quinn, K Meetze, P Bazinet, M DuPont, B Krawiec, K Kriksciukaite, C Lemelin, P LimSoo, H Oller, M Ramstack, D Rockwood, R Shinde, S Singh, B White, T AuYeung, C Dunbar, M Bilodeau, R Wooster
Title BTP-114: An albumin binding cisplatin prodrug with improved and sustained tumor growth inhibition
URL http://cancerres.aacrjournals.org/content/75/15_Supplement/4484
Abstract Text Cancer Res 2015;75(15 Suppl):Abstract nr 4484

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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
BTP-114 BTP-114 0 1
Drug Name Trade Name Synonyms Drug Classes Drug Description
BTP-114 BTP 114 BTP-114 is a prodrug of cisplatin that has prolonged plasma circulation time and increased tumor distribution, which leads to improved anti-tumor activity (Cancer Res 2015;75(15 Suppl):Abstract nr 4484).
Gene Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References