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Authors | Kenneth B Adler, Indu Parikh, Anne Crews, Shijing Fang, Qi Yin, Brian Dickson | ||||||||||||
Title | Effect of an anti-MARCKS peptide (BIO-11006) on metastasis of lung cancer in vivo. | ||||||||||||
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URL | http://ascopubs.org/doi/abs/10.1200/JCO.2017.35.15_suppl.e23017 | ||||||||||||
Abstract Text | Journal of Clinical Oncology 35, no. 15_suppl |
Molecular Profile | Treatment Approach |
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Gene Name | Source | Synonyms | Protein Domains | Gene Description | Gene Role |
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Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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BIO-11006 | BIO11006 | BIO-11006 is a small peptide that inhibits myristoylated alanine-rich C kinase substrate (MARCKS), which may lead to inhibition of tumor cell metastasis (Journal of Clinical Oncology 35, no. 15_suppl, PMID: 27556883). |
Gene | Variant | Impact | Protein Effect | Variant Description | Associated with drug Resistance |
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Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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