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Authors | Kirsty Learmonth, Lynne Braidwood, Penella Woll and Joe Conner | ||||||||||||
Title | Cytokine responses following intrapleural administration of oncolytic HSV SEPREHVIR in patients with malignant pleural mesothelioma | ||||||||||||
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URL | http://cancerimmunolres.aacrjournals.org/content/4/1_Supplement/B033.short | ||||||||||||
Abstract Text | Cancer Immunol Res 2016;4(1 Suppl):Abstract nr B033 |
Molecular Profile | Treatment Approach |
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Gene Name | Source | Synonyms | Protein Domains | Gene Description | Gene Role |
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Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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Seprehvir | HSV1716 | Seprehvir (HSV1716) is a mutant herpes simplex virus type 1 that replicates specifically in cancer cells and induces anti-tumour immune response (Cancer Immunol Res 2016;4(1 Suppl):Abstract nr B033, PMID: 31570234). |
Gene | Variant | Impact | Protein Effect | Variant Description | Associated with drug Resistance |
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Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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