Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
Ref Type | |||||||||||||
PMID | |||||||||||||
Authors | X Li, C Abrahams, M Embry, A Yu, J Kahana, M Brown, RK Narla, L Barnes, E Schwartz, J Boylan, J Zawada, H Stephenson, M Bruhns, S Bussell, A Steiner, A Galan, T Kline, A Yam, R Stafford, H Hoffmann, S Matheny, V DeAlmeida, N Vasquez, H Heinsohn et. al. | ||||||||||||
Title | Targeting CD74 with Novel Antibody Drug Conjugates (ADCs) for the Treatment of B-Cell Non-Hodgkin's Lymphoma (NHL) | ||||||||||||
|
|||||||||||||
URL | http://www.bloodjournal.org/content/128/22/464?sso-checked=true | ||||||||||||
Abstract Text | Blood 2016 128 (22):464 |
Molecular Profile | Treatment Approach |
---|
Gene Name | Source | Synonyms | Protein Domains | Gene Description | Gene Role |
---|
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
STRO-001 | SP7675 | CD74 Antibody 3 | STRO-001 is an anti-CD74 antibody in conjugation with a cytotoxic agent that may specifically target CD74-positive tumor cells (Blood 2016 128 (22):464, PMID: 30701025). |
Gene | Variant | Impact | Protein Effect | Variant Description | Associated with drug Resistance |
---|
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|