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Authors | F Giles M Witcher B Brown | ||||||||||||
Title | NEO2734: A novel potent oral dual BET and P300/CBP inhibitor | ||||||||||||
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URL | https://academic.oup.com/annonc/article/29/suppl_8/mdy279.416/5140815 | ||||||||||||
Abstract Text | Ann Oncol, 29(suppl_8), Oct 2018, abstract 429P |
Molecular Profile | Treatment Approach |
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Gene Name | Source | Synonyms | Protein Domains | Gene Description | Gene Role |
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Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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NEO2734 | NEO 2734|EP31670|EP-31670|NEO-2734|EP36170 | BET Inhibitor (Pan) 32 CBP/p300 inhibitor 11 | NEO 2734 is a dual inhibitor of the BET and CBP/P300 which potentially inhibits tumor growth (Ann Oncol, 29(suppl_8), Oct 2018, abstract 429P, PMID: 32371576). |
Gene | Variant | Impact | Protein Effect | Variant Description | Associated with drug Resistance |
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Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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