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Ref Type
PMID
Authors F Giles M Witcher B Brown
Title NEO2734: A novel potent oral dual BET and P300/CBP inhibitor
URL https://academic.oup.com/annonc/article/29/suppl_8/mdy279.416/5140815
Abstract Text Ann Oncol, 29(suppl_8), Oct 2018, abstract 429P

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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
NEO2734 NEO2734 0 1
Drug Name Trade Name Synonyms Drug Classes Drug Description
NEO2734 NEO 2734|EP31670|EP-31670|NEO-2734|EP36170 BET Inhibitor (Pan) 32 CBP/p300 inhibitor 11 NEO 2734 is a dual inhibitor of the BET and CBP/P300 which potentially inhibits tumor growth (Ann Oncol, 29(suppl_8), Oct 2018, abstract 429P, PMID: 32371576).
Gene Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References