Reference Detail

Ref Type
PMID
Authors Tobias Kratzsch, Viktor Gruenwald, Peter Vajkoczy and Susanne Antje Kuhn
Title Use of axitinib, a new-generation tyrosine kinase inhibitor, to decrease glioblastoma growth despite primary resistance to the VEGF-antibody bevacizumab.
Journal J Clin Oncol
Vol 31
Issue 15 suppl 2077
Date May
URL http://meeting.ascopubs.org/cgi/content/abstract/31/15_suppl/2077
Abstract Text J Clin Oncol (Meeting Abstracts) May 2013 vol. 31 no. 15_suppl 2077

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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
Drug Name Trade Name Synonyms Drug Classes Drug Description
Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown brain glioblastoma multiforme not applicable Axitinib Preclinical Actionable In a preclinical study, Inlyta (axitinib) demonstrated efficacy in glioblastoma cells, including those resistant to Bevacizumab (J Clin Oncol (Meeting Abstracts) May 2013 vol. 31 no. 15_suppl 2077). detail...