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Ref Type
PMID
Authors Jeeyun Lee, Seung Kim, Sujin Lee, Se Hoon Park, Joon Oh Park, Jeong-Won Lee, Kyoung Mee Kim, Hukeun Lee, Sung Hong, Jung Yong Kim, Song-Jae Lee, Seong-Won Song, Jung Ju Kim, Young Suk Park, Ho Yeong Lim, Won Ki Kang, Do-Hyun Nam
Title First-in-human phase I trial of anti-hepatocyte growth factor (HGF) antibody (YYB101) in refractory solid tumor patients.
URL http://ascopubs.org/doi/abs/10.1200/JCO.2018.36.15_suppl.e14501
Abstract Text

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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
YYB-101 YYB-101 0 0
Drug Name Trade Name Synonyms Drug Classes Drug Description
YYB-101 YYB101|YYB 101 HGF Antibody 4 YYB-101 is a humanized monoclonal antibody that targets HGF, potentially resulting in decreased tumor growth (J Clin Onc. 2018 36:15_suppl, e14501, PMID: 31355133).
Gene Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References