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Ref Type
PMID
Authors Zezhou Wang, Peter Dove, David Rosa, Bolette Bossen, Simone Helke, Marilyse Charbonneau, Laura Brinen, Karen Dodge, Gloria H. Y. Lin, Carole Galligan, Natasja N. Viller, Mark Wong, Vivian Lee, Tina Catalano, Robert A. Uger, Malik Slassi, Jeff Winston
Title Preclinical characterization of a novel non-cyclic dinucleotide small molecule STING agonist with potent antitumor activity in mice
URL https://www.abstractsonline.com/pp8/#!/6812/presentation/5408
Abstract Text AACR Annual Meeting 2019, Abstract 3854

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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
TTI-10001 TTI-10001 0 0
Drug Name Trade Name Synonyms Drug Classes Drug Description
TTI-10001 TTI 10001|TTI10001 STING1 Agonist 19 TTI-10001 is a small molecule agonist of STING1 that may lead to activation of anti-tumor immunity (AACR Annual Meeting 2019, Abstract 3854).
Gene Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References