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PMID | (31694708) | ||||||||||||
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Title | 34th Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2019): part 2 : National Harbor, MD, USA. 10 November 2019. | ||||||||||||
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Abstract Text |
Molecular Profile | Treatment Approach |
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Gene Name | Source | Synonyms | Protein Domains | Gene Description | Gene Role |
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Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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ADG116 | ADG-116|ADG 116 | CTLA4 Antibody 29 Immune Checkpoint Inhibitor 147 | ADG116 is a human monoclonal antagonistic antibody against CTLA4, which may stimulate anti-tumor immune response (PMID: 31694708). | |
PY159 | PY-159|PY 159 | PY159 is a monoclonal antibody that binds to and activates TREM1 on tumor-associated myeloid cells, which may promote anti-tumor immune response (PMID: 31694708). |
Gene | Variant | Impact | Protein Effect | Variant Description | Associated with drug Resistance |
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Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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