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Ref Type
PMID
Authors Fredrik G Oberg, Karin Tunblad, Ana Slipicevic, Richard Bethell and Mark R Albertella
Title MIV-818 stimulates an antitumor immune response in vitro and enhances the effects of pembrolizumab
URL https://mct.aacrjournals.org/content/18/12_Supplement/C056.abstract
Abstract Text Mol Cancer Ther 2019;18(12 Suppl):Abstract nr C056.

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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
MIV-818 MIV-818 0 1
Drug Name Trade Name Synonyms Drug Classes Drug Description
MIV-818 MIV818|MIV 818 MIV-818 is a prodrug that is hydrolyzed in hepatocytes to troxacitabine triphosphate (TRX-TP), which may have immune modulating and anti-tumor effects (Mol Cancer Ther 2019;18(12 Suppl):Abstract nr C056.).
Gene Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References