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Ref Type
PMID
Authors Kuan-Chun Huang, Atsushi Endo, Shannon McGrath, Dinesh Chandra, Jiayi Wu, Dae-Shik Kim, Diana Albu, Christy Ingersoll, Karen Tendyke, Kara Loiacono, Thomas Noland, David Verbel, Chi Zhang, Ming-Hong Hao, Mark Matijevic, Vaishali Dixit, Renee R. Hukkanen, Janna Hutz, John Wang, Frank Fang, Xingfeng Bao, Donna Kolber-Simonds, Muzaffar Akram and Nadeem Sarwar
Title Discovery and characterization of E7766, a novel macrocycle-bridged STING agonist with pan-genotypic and potent antitumor activity through intravesical and intratumoral administration
URL https://cancerres.aacrjournals.org/content/79/13_Supplement/3269
Abstract Text Cancer Res 2019;79(13 Suppl):Abstract nr 3269

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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
E7766 E7766 0 2
Drug Name Trade Name Synonyms Drug Classes Drug Description
E7766 E-7766|E 7766 STING1 Agonist 19 E7766 is an agonist of STING, which may potentially activate anti-tumor immune response (Cancer Res 2019;79(13 Suppl):Abstract nr 3269).
Gene Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References