Reference Detail


Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at :

Ref Type
Authors Shih-Feng Cho, Liang Lin, Lijie Xing, Kenneth Wen, Tengteng Yu, Phillip A Hsieh, Yuyin Li, Nikhil C. Munshi, Joachim Wahl, Katja Matthes, Kenneth C. Anderson, Tara Chapman-Arvedson, Yu-Tzu Tai
Title AMG 701 Potently Induces Anti-Multiple Myeloma (MM) Functions of T Cells and IMiDs Further Enhance Its Efficacy to Prevent MM Relapse In Vivo
Abstract Text Blood (2019) 134 (Supplement_1): 135


  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"


  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
Drug Name Trade Name Synonyms Drug Classes Drug Description
Gene Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown multiple myeloma not applicable AMG 701 Preclinical - Patient cell culture Actionable In a preclinical study, AMG 701 treatment induced lysis of cells from patients with relapsed/refractory multiple myeloma in culture, and inhibited tumor growth in a cell line xenograft model reconstituted with human effector T-cells (Blood (2019) 134 (Supplement_1): 135). detail...
Unknown unknown multiple myeloma not applicable AMG 701 + Lenalidomide Preclinical Actionable In a preclinical study, AMG 701 and Revlimid (lenalidomide) combination treatment enhanced tumor growth inhibition and regression in a mouse model of multiple myeloma (Blood (2019) 134 (Supplement_1): 135). detail...