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Authors | Lee Rosen, Patricia LoRusso, Wen Wee Ma, Johathan Goldman, Amy Weise, A. Dimitrios Colevas, Alex Adjei, Salim Yazji, Angela Shen, Stuart Johnston, Mary R. Gates, Cheryl Jones, Luna Musib, Alex De Crespigny, Iris Chan, Branimir Sikic | ||||||||||||
Title | Abstract 4716: A first-in-human phase 1 study to evaluate the MEK1/2 inhibitor GDC-0973 administered daily in patients with advanced solid tumors | ||||||||||||
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URL | http://cancerres.aacrjournals.org/content/71/8_Supplement/4716.short | ||||||||||||
Abstract Text | Cancer Res 2011;71(8 Suppl):Abstract nr 4716 |
Molecular Profile | Treatment Approach |
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Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
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Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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Gene | Variant | Impact | Protein Effect | Variant Description | Associated with drug Resistance |
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Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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