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Authors | Munster, P. N., van der Noll, R., Voest, E. E., Dees, E. C., Tan, A. R., Specht, J. M., Falchook, G. S., Daud, A., Lolkema, M. P., Grilley-Olson, J. E., Yu, E. Y., Fu, S., Bergsland, E. K., Kleha, J., Peng, S., Smith, D. A., Lampkin, T. A., Schellens, J. | ||||||||||||
Title | Phase I first-in-human study of the PI3 kinase inhibitor GSK2126458 (GSK458) in patients with advanced solid tumors (study P3K112826). | ||||||||||||
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URL | http://hwmaint.meeting.ascopubs.org/cgi/content/abstract/29/15_suppl/3018 | ||||||||||||
Abstract Text |
Molecular Profile | Treatment Approach |
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Gene Name | Source | Synonyms | Protein Domains | Gene Description | Gene Role |
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Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
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Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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Gene | Variant | Impact | Protein Effect | Variant Description | Associated with drug Resistance |
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Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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