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Authors | Sanjeev Deva, Richard D. Baird, Nicola Cresti, Javier Garcia-Corbacho, Linda Hogarth, Eugene P. Frenkel, Keiko Kawaguchi, Akinori Arimura, Kirsteen Donaldson, John Posner, Debashis Sarker, Duncan Ian Jodrell, Ruth Plummer, James F. Spicer | ||||||||||||
Title | Phase I expansion of S-222611, a reversible inhibitor of EGFR and HER2, in advanced solid tumors, including patients with brain metastases | ||||||||||||
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URL | http://meetinglibrary.asco.org/content/148414-156 | ||||||||||||
Abstract Text | J Clin Oncol 33, 2015 (suppl; abstr 2511) |
Molecular Profile | Treatment Approach |
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Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
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Gene | Variant | Impact | Protein Effect | Variant Description | Associated with drug Resistance |
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Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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