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Ref Type
Authors TJ Wickham, J Reynolds, DC Drummond, DB Kirpotin, J Lahdenranta, SC Leonard, E Geretti, H Lee, S Klinz, BS Hendriks, K Olivier, I Eckelhofer, JW Park, CC Benz, VM Moyo, C Niyikiza, and UB. Nielsen
Title Abstract P3-14-09: Preclinical Safety and Activity of MM-302, a HER2-Targeted Liposomal Doxorubicin Designed To Have an Improved Safety and Efficacy Profile over Approved Anthracyclines
Journal Cancer Research
Abstract Text Cancer Res December 15, 2010 70; P3-14-09


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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
Drug Name Trade Name Synonyms Drug Classes Drug Description
Gene Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
ERBB2 over exp stomach cancer predicted - sensitive MM-302 Preclinical Actionable In a preclinical study, ERBB2 (HER2) over expressing gastric cancer xenograft models demonstrated anti-tumor activity when treated with MM-302 (Cancer Res December 15, 2010 70; P3-14-09). detail...