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Authors | Robert R. McWilliams, Andrew H. Ko, E. Gabriela Chiorean, Eunice Lee Kwak, Heinz-Josef Lenz, Paul I. Nadler, Debra L Wood, Masamoto Fujimori, Kohei Morita, Tetsuhi Inada, Hiroyuki Kouji | ||||||||||||
Title | A phase Ib dose-escalation study of PRI-724, a CBP/beta-catenin modulator, plus gemcitabine (GEM) in patients with advanced pancreatic adenocarcinoma (APC) as second-line therapy after FOLFIRINOX or FOLFOX. | ||||||||||||
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URL | http://meetinglibrary.asco.org/content/148137-156 | ||||||||||||
Abstract Text | J Clin Oncol 33, 2015 (suppl; abstr e15270) |
Molecular Profile | Treatment Approach |
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Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
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Gene | Variant | Impact | Protein Effect | Variant Description | Associated with drug Resistance |
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Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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