Reference Detail

Ref Type
PMID
Authors H. H. Doss, S. F. Jones, J. R. Infante, D. R. Spigel, N. Willcutt, R. Lamar, J. Barton, M. Keegan and H. A. Burris, III
Title A phase I trial of romidepsin in combination with gemcitabine in patients with pancreatic and other advanced solid tumors
Journal Journal of Clinical Oncology
Vol
Issue
Date
URL http://meeting.ascopubs.org/cgi/content/short/26/15_suppl/2567
Abstract Text J Clin Oncol (Meeting Abstracts) May 2008 vol. 26 no. 15_suppl 2567

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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
Drug Name Trade Name Synonyms Drug Classes Drug Description
Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown Advanced Solid Tumor not applicable Romidepsin Phase I Actionable In a Phase I trial, Istodax (romidepsin), in combination with Gemzar (gemcitabine), demonstrated safety and some efficacy in patients with a variety of advanced solid tumors (J Clin Oncol, May 2008 vol. 26 no. 15_suppl 2567). detail...