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Ref Type
PMID
Authors Hope S. Rugo, Abhijit Barve, Cornelius F. Waller, Miguel Hernandez-Bronchud, Jay Herson, Jinyu Yuan, Alexey Manikhas, Igor Bondarenko, Guzel Mukhametshina, Gia Nemsadze, Joseph D. Parra, Maria Luisa T. Abesamis Tiambeng, Kakhaber Baramidze et al
Title Heritage: A phase III safety and efficacy trial of the proposed trastuzumab biosimilar Myl-1401O versus Herceptin.
URL http://meetinglibrary.asco.org/content/162159-176
Abstract Text J Clin Oncol 34, 2016 (suppl; abstr LBA503)

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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
MYL-1401O MYL-1401O 0 0
Drug Name Trade Name Synonyms Drug Classes Drug Description
MYL-1401O HER2 (ERBB2) Antibody 72 MYL-1401O is a biosimilar of trastuzumab that demonstrates comparable safety and efficacy in ERBB2 (HER2)-positive breast cancer patients (J Clin Oncol 34, 2016 (suppl; abstr LBA503), PMID: 32660375).
Gene Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References