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Authors | Alex A. Adjei, Grace K. Dy, Yujie Zhao, Wen Wee Ma, Mateusz Opyrchal, Hatoon Bakhribah, Sandra M Jacob, Corrie O'Hara, Askia Dozier, Natasa Cmiljanovic, Barbara Todaro, William E. Brady, Debora Schmitz, Sasa Dimitrijevic | ||||||||||||
Title | A phase 1 study of the PI3K/mTOR inhibitor PQR309 evaluating safety, pharmacokinetics (PK) and pharmacodynamics (PD) in patients (pts) with advanced solid tumors. | ||||||||||||
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URL | http://meetinglibrary.asco.org/content/170190-176 | ||||||||||||
Abstract Text | J Clin Oncol 34, 2016 (suppl; abstr 2560) |
Molecular Profile | Treatment Approach |
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Gene Name | Source | Synonyms | Protein Domains | Gene Description | Gene Role |
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Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
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Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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Gene | Variant | Impact | Protein Effect | Variant Description | Associated with drug Resistance |
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Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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