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Ref Type
Authors Yasuhide Yamada, Tomohiro Nishina, Satoru Iwasa, Kohei Shitara, Kei Muro, Taito Esaki, Shuichi Hironaka, Kensei Yamaguchi, Nozomu Machida, Taroh Satoh, Anja von Heydebreck, Hiroyuki Achiwa, Toshihiko Doi
Title A phase I dose expansion trial of avelumab (MSB0010718C), an anti-PD-L1 antibody, in Japanese patients with advanced gastric cancer.
Journal J Clin Oncol
Abstract Text J Clin Oncol 33, 2015 (suppl; abstr 4047)


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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
Drug Name Trade Name Synonyms Drug Classes Drug Description
Gene Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown stomach cancer not applicable Avelumab Phase I Actionable In a Phase I trial, Bavencio (avelumab) treatment resulted in partial response in 27% (3/11) of patients with advanced gastric cancer (J Clin Oncol 33, 2015 (suppl; abstr 4047)). detail...