Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
Ref Type | |||||||||||||
PMID | |||||||||||||
Authors | J. Bendell, G.S. Eckhardt, H.S. Hochster, V.K. Morris, J. Strickler, A.M. Kapoun, M. Wang, L. Xu, K. McGuire, J. Dupont, L. Faoro, P. Munster | ||||||||||||
Title | Initial results from a phase 1a/b study of OMP-131R10, a first-in-class anti-RSPO3 antibody, in advanced solid tumors and previously treated metastatic colorectal cancer (CRC) | ||||||||||||
|
|||||||||||||
URL | https://publications.oncomed.com/Ph-1ab-OMP-131R10-anti-RSPO3-adv-solid-tumor-prev-treat-met-CRC-2016-EORTC-NCI-AACR.pdf | ||||||||||||
Abstract Text | https://publications.oncomed.com/Ph-1ab-OMP-131R10-anti-RSPO3-adv-solid-tumor-prev-treat-met-CRC-2016-EORTC-NCI-AACR.pdf |
Molecular Profile | Treatment Approach |
---|
Gene Name | Source | Synonyms | Protein Domains | Gene Description | Gene Role |
---|
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|
Gene | Variant | Impact | Protein Effect | Variant Description | Associated with drug Resistance |
---|
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|