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Authors | Han HS Sook, Diéras V, Robson ME E, Palácová M, Marcom PK Kelly, Jager A, Bondarenko I, Citrin D, Campone M, Telli ML, Domchek SM M, Friedlander M, Kaufman B, Ratajczak C, Coates A, Bonnet P, Qin Q, Qian J, Giranda VL et al. | ||||||||||||
Title | Efficacy and tolerability of veliparib (V, ABT-888) in combination with carboplatin (C) and paclitaxel (P) vs placebo (Plc)+C/P in patients (pts) with BRCA1 or BRCA2 mutations and metastatic breast cancer- A randomized, phase 2 study | ||||||||||||
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URL | https://cancerres.aacrjournals.org/content/77/4_Supplement/S2-05 | ||||||||||||
Abstract Text | SABCS, 2016, Abstract S2-05 |
Molecular Profile | Treatment Approach |
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Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
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Gene | Variant | Impact | Protein Effect | Variant Description | Associated with drug Resistance |
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Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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