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Authors | Jeffrey R. Infante, Philippe L. Bedard, Geoffrey Shapiro, Todd Michael Bauer, Amy Prawira, Oscar Laskin, Marla Weetall, John Baird, Art Branstrom, Edward O'Mara, Robert J. Spiegel; Sarah Cannon | ||||||||||||
Title | Phase 1 results of PTC596, a novel small molecule targeting cancer stem cells (CSCs) by reducing levels of BMI1 protein. | ||||||||||||
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URL | http://abstracts.asco.org/199/AbstView_199_189820.html | ||||||||||||
Abstract Text | J Clin Oncol 35, 2017 (suppl; abstr 2574) |
Molecular Profile | Treatment Approach |
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Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
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Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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Gene | Variant | Impact | Protein Effect | Variant Description | Associated with drug Resistance |
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Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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