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Authors | Rebecca Alexandra Dent, Sung-Bae Kim, Seock-Ah Im, Marc Espie, Sibel Blau, Antoinette R. Tan, Steven Isakoff, Mafalda Oliveira, Cristina Saura, Matthew Wongchenko, Amy V. Kapp, Wai Y. Chan, Stina M. Singel, Daniel J. Maslyar, Jose Baselga | ||||||||||||
Title | LOTUS (NCT02162719): A double-blind placebo (PBO)-controlled randomized phase II trial of first-line ipatasertib (IPAT) + paclitaxel (P) for metastatic triple-negative breast cancer (TNBC). | ||||||||||||
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URL | http://abstracts.asco.org/199/AbstView_199_183382.html | ||||||||||||
Abstract Text | J Clin Oncol 35, 2017 (suppl; abstr 1009) |
Molecular Profile | Treatment Approach |
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Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
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Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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Gene | Variant | Impact | Protein Effect | Variant Description | Associated with drug Resistance |
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Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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