Reference Detail

Ref Type
Authors Elizabeth Susan Gabitzsch, Michael A. Morse, H. Kim Lyerly, Joseph Balint, Frank Jones
Title Immunotherapeutic treatment of metastatic colorectal cancer using ETBX-011.
Journal Journal of Clinical Oncology
Abstract Text Journal of Clinical Oncology 32, no. 15_suppl (May 2014) 3093-3093


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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
Drug Name Trade Name Synonyms Drug Classes Drug Description
ETBX-011 ETBX-011 is an engineered adenoviral vaccine encoding human carcinoembryonic antigen that may stimulate anti-tumor immunity (Journal of Clinical Oncology 32, no. 15_suppl (May 2014) 3093-3093).
Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown colorectal cancer not applicable ETBX-011 Phase Ib/II Actionable In a Phase I/II trial, ETBX-011 treatment resulted in an overall survival of 11 months, and survival at 12 months follow-up in 48% of patients with metastatic colorectal cancer (Journal of Clinical Oncology 32, no. 15_suppl (May 2014) 3093-3093; NCT01147965.). detail...