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Ref Type
PMID
Authors A. Naing, S. Leong, M.J. Pishvaian, A.R.A. Razak, A. Mahipal, J. Berlin, D. Cho, W. Senapedis, S. Shacham, M. Kauffman, J. Ellis, J. Meade, E. Baloglu
Title A first in human phase 1 study of KPT-9274, a first in class dual inhibitor of PAK4 and NAMPT, in patients with advanced solid malignancies or NHL
URL https://www.annalsofoncology.org/article/S0923-7534(20)37794-2/fulltext
Abstract Text Ann Oncol 2017, Vol 28, Suppl 5, Abstract # 374PD

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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
Drug Name Trade Name Synonyms Drug Classes Drug Description
Gene Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References