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Authors | N. Turner, E. Alarcon, A. Armstrong, M. Philco, Y.A. Lopez Chuken, M-P. Sablin, K. Tamura, A. Gomez Villanueva, J.A. Pe ?rez-Fidalgo, A. Foxley, J. Lindemann, R. Maudsley, E. Outhwaite, M. Pass, P. Rugman, G. Schiavon, M. Oliveira | ||||||||||||
Title | BEECH: A randomised Phase 2 study assessing the efficacy of AKT inhibitor AZD5363 combined with paclitaxel in patients with ER+ve advanced or metastatic breast cancer, and in a PIK3CA mutant sub-population | ||||||||||||
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URL | https://www.annalsofoncology.org/article/S0923-7534(20)37665-1/fulltext | ||||||||||||
Abstract Text | Ann Oncol 2017, Vol 28, Suppl 5, Abstract # 241PD |
Molecular Profile | Treatment Approach |
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Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
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Gene | Variant | Impact | Protein Effect | Variant Description | Associated with drug Resistance |
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Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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