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Therapy Name | CTX-471 |
Synonyms | |
Therapy Description |
CTX-471 is an agonistic antibody that binds to CD137 (4-1BB), which potentially activates immune cells resulting in reduced tumor growth (PMID: 32161196). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
CTX-471 | CTX471|CTX 471|anti-4-1BB agonistic monoclonal antibody | TNFRSF9 Antibody 30 | CTX-471 is an agonistic antibody that binds to CD137 (4-1BB), which potentially activates immune cells resulting in reduced tumor growth (PMID: 32161196). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT03881488 | Phase I | CTX-471 | Study of CTX-471 in Patients Post PD-1/PD-L1 Inhibitors in Metastatic or Locally Advanced Malignancies | Recruiting | USA | 0 |