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Therapy Name | GDC-6036 |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
GDC-6036 | GDC6036|GDC 6036 | KRAS G12C inhibitor 23 | GDC-6036 is a selective inhibitor of KRAS G12C that blocks downstream signaling, and may lead to anti-tumor activity (NCI Drug Dictionary). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT04449874 | Phase I | Atezolizumab + GDC-6036 Bevacizumab + GDC-6036 Cetuximab + GDC-6036 Erlotinib + GDC-6036 GDC-6036 | A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Participants With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation | Recruiting | USA | ITA | ESP | CAN | BEL | 10 |