Therapy Detail

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Therapy Name JBH492
Synonyms
Therapy Description

JBH492 is an antibody-drug conjugate consisting of an antibody that targets CC chemokine receptor 7 present on tumor cells and conjugated to the maytanisoid DM4, which may lead to inhibition of tumor cell proliferation (NCI Drug Ductionary).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
JBH492 JBH 492|JBH-492|Anti-CCR7 ADC JBH492 JBH492 is an antibody-drug conjugate consisting of an antibody that targets CC chemokine receptor 7 present on tumor cells and conjugated to the maytanisoid DM4, which may lead to inhibition of tumor cell proliferation (NCI Drug Ductionary).

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  • Case insensitive filtering will display rows if any text in any cell matches the filter term
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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04240704 Phase I JBH492 Safety and Preliminary Efficacy of JBH492 Monotherapy in Patients With Chronic Lymphocytic Leukemia (CLL) and Non-Hodgkin's Lymphoma (NHL) Recruiting USA | ESP | DEU 5


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