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Therapy Name | CD19-PD-1/CD28-CAR T cells |
Synonyms | |
Therapy Description |
CD19-PD-1/CD28-CAR T cells consist of autologous T-lymphomcytes engineered to produce a chimeric antigen receptor (CAR) with an anti-CD19 fragment and a PD-1/CD28 chimeric switch-receptor, which may lead to potential cytotoxic activity against tumor cells expressing PD-L1 (PMID: 33028589). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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CD19-PD-1/CD28-CAR T cells | CD19-PD-1/CD28-CAR T cells consist of autologous T-lymphomcytes engineered to produce a chimeric antigen receptor (CAR) with an anti-CD19 fragment and a PD-1/CD28 chimeric switch-receptor, which may lead to potential cytotoxic activity against tumor cells expressing PD-L1 (PMID: 33028589). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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