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|Therapy Name||Camptothecin + KU-59403|
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|Camptothecin||21,22-Secocamptothecin-21-oic acid lactone|Camptothecine||TOPO1 inhibitor 9||Camptothecin is a natural product alkaloid topoisomerase I inhibitor from which irinotecan and topotecan are derived (PMID: 16990856, PMID: 32585151)|
|KU-59403||KU59403|KU 59403||ATM Inhibitor 11||KU-59403 is an ATM inhibitor, which upon inhibition of Atm may lead to increased sensitivity to chemotherapuetic agents such as those inducing double strand breaks, and radiotherapy, subsequently resulting in cytotoxicity and antitumor activity (PMID: 23512991).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|