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Therapy Name | RO5126766 + VS-4718 |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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RO5126766 | VS-6766|CH5126766 | MEK inhibitor (Pan) 22 MEK1 Inhibitor 20 MEK2 Inhibitor 18 RAF Inhibitor (Pan) 20 | RO5126766 (VS-6766) is dual RAF-MEK1/2 inhibitor with effectiveness against both BRAF and RAS mutated cells (PMID: 25422890). | |
VS-4718 | FAK inhibitor 13 | VS-4718 is a focal adhesion kinase (FAK) inhibitor, which prevents FAK autophosphorylation and activation of downstream YAP1 and Hippo pathway signaling, potentially resulting in decreased tumor cell proliferation, migration, and survival (PMID: 30773340). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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