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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|BLU-701||BLU701|BLU 701||EGFR Inhibitor 4th gen 3||BLU-701 is a reversible EGFR inhibitor that blocks the activity of mutant forms of EGFR, including C797S, while sparing wild-type EGFR, which results in reduced downstream signaling and potentially leads to decreased tumor growth (Cancer Res 2021;81(13_Suppl):Abstract nr 1262).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|
|NCT05153408||Phase Ib/II||BLU-701 BLU-701 + Osimertinib BLU-701 + Carboplatin + Pemetrexed Disodium||(HARMONY) Study of BLU-701 in EGFR-mutant NSCLC||Recruiting||USA||0|